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46-Dioxoheptanoic acid

CAS No. 51568-18-4

46-Dioxoheptanoic acid( Succinylacetone )

Catalog No. M21430 CAS No. 51568-18-4

46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    46-Dioxoheptanoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
  • Description
    46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
  • In Vitro
    4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture.
  • In Vivo
    ——
  • Synonyms
    Succinylacetone
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    51568-18-4
  • Formula Weight
    158.15
  • Molecular Formula
    C7H10O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:1 mg/mL (632.31 mM)
  • SMILES
    CC(CC(CCC(O)=O)=O)=O
  • Chemical Name
    46-dioxoheptanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ebert PS et al. Succinylacetone a potent inhibitor of heme biosynthesis: effect on cell growth heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88(4):1382-90.
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